Fioricet Interaction
A total of 586 drugs are known to interact with Fioricet (acetaminophen / butalbital / caffeine) categorized as 45 major, 490 moderate, and 51 minor interactions.
Most frequently checked interactions
View interaction reports for Fioricet (acetaminophen / butalbital / caffeine) and the medicines listed below.
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-
- Ambien (zolpidem)
- baclofen
- clonazepam
- Cymbalta (duloxetine)
- Flexeril (cyclobenzaprine)
- gabapentin
- ibuprofen
- Klonopin (clonazepam)
- levothyroxine
- lisinopril
- Lyrica (pregabalin)
- Norco (acetaminophen / hydrocodone)
- omeprazole
- prednisone
- Topamax (topiramate)
- tramadol
- trazodone
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Zofran (ondansetron)
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Medications known to interact with Fioricet (acetaminophen / butalbital / caffeine)
Note: Showing generic names only.
A
-
-
-
- abametapir topical
- abemaciclib
- acalabrutinib
- acebutolol
- acetylcarbromal
- adenosine
- aldesleukin
- alfentanil
- alfuzosin
- alosetron
- alpelisib
- alprazolam
- altretamine
- aminophylline
- amitriptyline
- amlodipine
- amobarbital
- amoxapine
- amprenavir
- anagrelide
- anisindione
- apalutamide
- apixaban
- apomorphine
- apraclonidine ophthalmic
- apremilast
- aprepitant
- aripiprazole
- armodafinil
- asenapine
- asparaginase erwinia chrysanthemi
- asparaginase escherichia coli
- aspirin
- atazanavir
- atorvastatin
- atropine
- avanafil
- avapritinib
- axitinib
- azatadine
- azilsartan medoxomil
-
-
B
-
-
-
- baclofen
- bedaquiline
- belladonna
- bendamustine
- benoxinate ophthalmic
- benzocaine topical
- benztropine
- bepridil
- betamethasone
- bexarotene
- biperiden
- black cohosh
- boceprevir
- bortezomib
- bosutinib
- brentuximab
- brexanolone
- brexpiprazole
- brigatinib
- brimonidine ophthalmic
- brimonidine topical
- brivaracetam
- bromocriptine
- brompheniramine
- buprenorphine
- bupropion
- buspirone
- busulfan
- butabarbital
- butorphanol
-
-
C
-
-
-
- cabazitaxel
- cabozantinib
- calaspargase pegol
- calcifediol
- calcitriol
- canagliflozin
- cannabidiol
- cannabis
- capmatinib
- carbamazepine
- carbetapentane
- carbinoxamine
- cariprazine
- carisoprodol
- carvedilol
- caspofungin
- cenobamate
- ceritinib
- cetirizine
- cevimeline
- charcoal
- chlophedianol
- chloral hydrate
- chloramphenicol
- chlordiazepoxide
- chlorotrianisene
- chlorphenesin
- chlorpheniramine
- chlorpromazine
- chlorzoxazone
- cholecalciferol
- cholestyramine
- cimetidine
- ciprofloxacin
- citalopram
- clemastine
- clevidipine
- clidinium
- clobazam
- clofarabine
- clomipramine
- clonazepam
- clonidine
- clorazepate
- clozapine
- cobimetinib
- cocaine nasal
- cocaine topical
- codeine
- conjugated estrogens
- copanlisib
- corticorelin
- corticotropin
- cortisone
- cosyntropin
- crizotinib
- cyclobenzaprine
- cycloserine
- cyclosporine
- cyproheptadine
-
-
D
-
-
-
- daclizumab
- dantrolene
- dapsone
- dapsone topical
- darifenacin
- darolutamide
- darunavir
- dasatinib
- deferasirox
- delavirdine
- desipramine
- desvenlafaxine
- deutetrabenazine
- dexamethasone
- dexbrompheniramine
- dextromethorphan
- dezocine
- diazepam
- dibucaine topical
- dicumarol
- dicyclomine
- diflunisal
- digitoxin
- dihydroergotamine
- dihydrotachysterol
- diltiazem
- diphenhydramine
- dipyridamole
- disopyramide
- disulfiram
- divalproex sodium
- docetaxel
- dolutegravir
- donepezil
- doravirine
- doxazosin
- doxepin
- doxepin topical
- doxercalciferol
- doxorubicin
- doxorubicin liposomal
- doxycycline
- doxylamine
- dronabinol
- dronedarone
- droperidol
- drospirenone
- duloxetine
- duvelisib
-
-
E
-
-
-
- echinacea
- efavirenz
- elagolix
- eliglustat
- encorafenib
- enoxacin
- entacapone
- entrectinib
- enzalutamide
- epirubicin
- ergocalciferol
- ergonovine
- ergotamine
- erlotinib
- escitalopram
- esketamine
- eslicarbazepine
- estazolam
- esterified estrogens
- estradiol
- estradiol topical
- estrone
- estropipate
- eszopiclone
- ethanol
- ethinyl estradiol
- ethosuximide
- ethotoin
- etonogestrel
- etravirine
- everolimus
- exemestane
- ezogabine
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F
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-
-
- felbamate
- fenofibrate
- fenoldopam
- fenoprofen
- fentanyl
- fesoterodine
- flavoxate
- flibanserin
- fludrocortisone
- fluoxetine
- fluphenazine
- flurazepam
- fluvoxamine
- fosamprenavir
- fosaprepitant
- fosphenytoin
- fostamatinib
- fostemsavir
- furazolidone
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-
G
-
-
-
- gabapentin
- gabapentin enacarbil
- gefitinib
- gilteritinib
- givosiran
- glasdegib
- glycerol phenylbutyrate
- glycopyrrolate
- grepafloxacin
- griseofulvin
- guanfacine
-
-
H
-
-
-
- halazepam
- haloperidol
- hemin
- heroin
- hydrocodone
- hydrocortisone
- hydromorphone
- hydroxyprogesterone
- hyoscyamine
-
-
I
-
-
-
- ibrutinib
- idelalisib
- ifosfamide
- iloperidone
- imatinib
- imipramine
- indinavir
- infigratinib
- interferon beta-1a
- interferon beta-1b
- irinotecan
- irinotecan liposomal
- isavuconazonium
- isocarboxazid
- isoniazid
- isradipine
- ivabradine
- ivacaftor
- ixabepilone
- ixazomib
-
-
K
-
-
-
- kava
- ketamine
-
-
L
-
-
-
- labetalol
- lamotrigine
- lapatinib
- larotrectinib
- lasmiditan
- lefamulin
- leflunomide
- lemborexant
- lesinurad
- levamlodipine
- levetiracetam
- levobupivacaine
- levocetirizine
- levomethadyl acetate
- levonorgestrel
- levorphanol
- levothyroxine
- lidocaine
- lidocaine ophthalmic
- lidocaine topical
- linagliptin
- linezolid
- liothyronine
- liotrix
- liraglutide
- lithium
- lofexidine
- lomitapide
- lonafarnib
- lorazepam
- lorlatinib
- losartan
- loxapine
- lumateperone
- lurasidone
- lurbinectedin
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-
M
-
-
-
- macimorelin
- macitentan
- maprotiline
- maraviroc
- medroxyprogesterone
- mefloquine
- megestrol
- melatonin
- mepenzolate
- meperidine
- mephenytoin
- mephobarbital
- mesoridazine
- metaxalone
- methadone
- methdilazine
- methocarbamol
- methohexital
- methotrexate
- methotrimeprazine
- methoxyflurane
- methscopolamine
- methsuximide
- methyldopa
- methylene blue
- methylergonovine
- methylprednisolone
- methysergide maleate
- metoclopramide
- metoprolol
- metronidazole
- metyrosine
- mibefradil
- midazolam
- midostaurin
- mifepristone
- mipomersen
- mirabegron
- mirtazapine
- mitotane
- modafinil
- molindone
- montelukast
- morphine
- morphine liposomal
-
-
N
-
-
-
- nabilone
- nalbuphine
- nalidixic acid
- naloxegol
- naltrexone
- nebivolol
- nefazodone
- nelfinavir
- nicardipine
- nicotine
- nifedipine
- nilotinib
- nimodipine
- nisoldipine
- nitisinone
- norethindrone
- norfloxacin
- norgestrel
- nortriptyline
-
-
O
-
-
-
- obeticholic acid
- olanzapine
- olaparib
- oliceridine
- olopatadine nasal
- opicapone
- opium
- orphenadrine
- osilodrostat
- osimertinib
- ospemifene
- oxazepam
- oxcarbazepine
- oxtriphylline
- oxybutynin
- oxycodone
- oxymorphone
- ozanimod
-
-
P
-
-
-
- paclitaxel
- paclitaxel protein-bound
- palbociclib
- paliperidone
- panobinostat
- paraldehyde
- paramethadione
- paricalcitol
- paroxetine
- pazopanib
- pegaspargase
- peginterferon beta-1a
- pemigatinib
- penbutolol
- pentazocine
- pentobarbital
- perampanel
- pergolide
- perphenazine
- pexidartinib
- phenacemide
- phenelzine
- phenobarbital
- phensuximide
- phenytoin
- pimavanserin
- pimozide
- pitolisant
- pneumococcal 13-valent vaccine
- pneumococcal 7-valent vaccine
- ponatinib
- pramipexole
- praziquantel
- prazosin
- prednisolone
- prednisone
- pregabalin
- prilocaine
- primidone
- probenecid
- procarbazine
- prochlorperazine
- procyclidine
- progesterone
- progesterone topical
- promazine
- promethazine
- propafenone
- propantheline
- proparacaine ophthalmic
- propiomazine
- propoxyphene
- propranolol
- protriptyline
- pyridoxine
- pyrilamine
-
-
Q
-
-
-
- quazepam
- quetiapine
- quinestrol
- quinidine
- quinine
-
-
R
-
-
-
- ramelteon
- ranitidine
- ranitidine bismuth citrate
- ranolazine
- rasagiline
- regadenoson
- relugolix
- remdesivir
- remifentanil
- remimazolam
- repaglinide
- ribociclib
- rifampin
- rilpivirine
- riluzole
- riociguat
- ripretinib
- risperidone
- ritonavir
- rivaroxaban
- rolapitant
- ropinirole
- ropivacaine
- rotigotine
- rucaparib
- rufinamide
- ruxolitinib
-
-
S
-
-
-
- saquinavir
- saxagliptin
- scopolamine
- secobarbital
- selpercatinib
- selumetinib
- sertraline
- sibutramine
- sildenafil
- silodosin
- sirolimus
- sodium nitrite
- sodium oxybate
- sodium salicylate
- solifenacin
- sonidegib
- sorafenib
- sotorasib
- st. john’s wort
- stiripentol
- sufentanil
- sulfinpyrazone
- sunitinib
- suvorexant
-
-
T
-
-
-
- tacrolimus
- tadalafil
- tafamidis
- tamoxifen
- tamsulosin
- tapentadol
- tasimelteon
- tazemetostat
- telaprevir
- telithromycin
- telmisartan
- temazepam
- temsirolimus
- tepotinib
- terazosin
- terbinafine
- teriflunomide
- tetrabenazine
- tetracaine ophthalmic
- tetracaine topical
- thalidomide
- theophylline
- thiabendazole
- thiethylperazine
- thioguanine
- thiopental
- thioridazine
- thiothixene
- thyroid desiccated
- tiagabine
- ticagrelor
- timolol
- tinidazole
- tipranavir
- tizanidine
- tofacitinib
- tolcapone
- tolterodine
- tolvaptan
- topiramate
- topotecan
- toremifene
- trabectedin
- tramadol
- tranylcypromine
- trazodone
- triamcinolone
- triazolam
- trifluoperazine
- triflupromazine
- trihexyphenidyl
- trimeprazine
- trimethadione
- trimethobenzamide
- trimipramine
- tripelennamine
- triprolidine
- trospium
- trovafloxacin
- tucatinib
-
-
U
-
-
-
- ubrogepant
- ulipristal
-
-
V
-
-
-
- valbenazine
- valerian
- valproic acid
- vemurafenib
- venetoclax
- venlafaxine
- verapamil
- vigabatrin
- vilazodone
- viloxazine
- voriconazole
- vortioxetine
-
-
W
-
-
-
- warfarin
-
-
Z
-
-
-
- zaleplon
- zanubrutinib
- ziconotide
- zidovudine
- ziprasidone
- zolpidem
- zonisamide
-
-
Fioricet (acetaminophen / butalbital / caffeine) alcohol/food interactions
There are 6 alcohol/food interactions with Fioricet (acetaminophen / butalbital / caffeine)